Postdoctoral Research Associate I - III, Cancer Immunology ( Multiple Positions )

Posting Number: req22454

Position Description:

The Theodorescu Lab within the University of Arizona Cancer Center (UACC) is looking to hire a postdoctoral researcher with a strong background in cancer immunology and the tumor microenvironment (TME). This project will be characterizing the tumor microenvironment of bladder cancer, with emphasis on mechanisms of immune evasion orchestrated by tumor cells while also identifying immune system agonists or antagonists that modulate tumor behavior in vivo. To dissect cancer-specific vulnerabilities, we will combine techniques of biochemistry, molecular biology, and Crispr/Cas9 technologies, functional genomic approaches (loss of function/synthetic lethal), next generation sequencing including single cell RNA sequencing, together with the use of innovative mouse models we have developed. Examples of the type of work that will be undertaken can be seen by our papers by Abdel-Hafiz (Nature. 2023 Jul;619(7970):624-631), Gouin (Nature Commun. 2021; 12;12(1)), Agarwal (Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e) and Tu (Science Adv. 2019; 20;5(2)). Our final goal is to identify novel biomarkers and interventions for cancer that will improve patient outcomes.

This individual would join our exciting cancer research group. The successful candidate will be a driven, creative, team-oriented individual with a passion for helping to discover fundamental cancer biology mechanisms that have potential clinical impact and thus can be moved eventually towards a clinical setting. We employ many different in vitro and in vivo approaches and seek individuals with a strong background in cell and molecular immunology.

Outstanding UA Benefits! The University of Arizona is an Equal Opportunity Employer Vets/Disabled.

Minimum Qualifications:

Doctorate (PhD, MD or MD/PhD) in immunology or area directly related to field of research specialization.
Up to 3 years of relevant post-doctoral experience